Physico Chemical Principles & Applications of Fluorine
نویسنده
چکیده
Molecular & Cellular Imaging is “the in-vivo characterization and measurement of biological processes at the cellular and molecular level” and aims to image molecular abnormalities associated with diseases and to monitor cell assemblys such as macrophages or stem cells. MRI (magnetic resonance imaging), PET, and optical imaging are currently the modalities of choice, which can be used in the living system. Among the different non-invasive modalities, MRI has a number of characteristics that makes it an ideal candidate: (1) an extraordinary 3-dimensional capabilities, (2) a superb spatial and temporal resolution and (3) a high safety profile. In addition, MRI appears very attractive, since current MRI protocols already provide anatomic, functional and biochemical information in excellent image quality. Combining this high spatial resolution/high contrast imaging modality with specific MR imaging agents is current focus in many research laboratories, in particular small animal imaging centers, worldwide.
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